Ginko Biloba
Ginkgo biloba is an herbal supplement most commonly marketed for cognition, circulation, and sometimes sexual function. Most products use standardized leaf extracts (often framed around terpene lactones and flavone glycosides), and the general “use case” people cite is improved blood flow/microcirculation and antioxidant-type effects. Because of that circulation framing, some people try ginkgo as a mild option for ED or genital sensation issues—often with the idea that it might help vascular function or arousal responsiveness rather than directly changing hormones.
In terms of overlap with PFS/PSSD/PAS discussions, ginkgo is usually treated as a lower-impact intervention. It’s not typically discussed as an anti-androgen or a strong serotonergic agent. Where it can matter is that it still acts on CNS/vascular signaling, and for some people that can translate into noticeable (but often subtle) changes in alertness, anxiety, sleep, headaches, or libido—positive or negative.
Anecdotes (Community Reports):
https://www.reddit.com/r/PSSD/comments/vw4fk8/ginkgo/
https://www.reddit.com/r/PSSD/comments/121sk9f/has_anyone_tried_a_megadose_of_gingko/
https://www.reddit.com/r/PSSD/comments/wuhhs2/ginkgo_biloba_for_antidepressantinduced_sexual/
How to Interpret This Page
This page summarizes anecdotal reports and community observations, not medical evidence. “Risk” here refers to how frequently severe or prolonged symptom worsening is reported, not to proven causation or population-wide probability. Individual responses vary widely, and absence of issues in some users does not rule out significant reactions in others.
Community Reports: Mixed Outcomes & Variable Risk Signal
Overall pattern: In community discussions, ginkgo is most often described as not moving the needle. Some people report transient improvements—slightly better erection quality, mild increase in genital blood flow sensation, or a subtle cognitive “brightness”—but these reports tend to be inconsistent and not durable. Many report no meaningful change at all.
Flares/worsening: Severe or lasting worsening is not a common theme, but flares do get mentioned: headaches, jitteriness/anxiety, sleep disruption, feeling “wired,” or a general sense of being slightly off. When negative reactions are reported, they’re usually framed as reversible after stopping rather than a major baseline shift.
Practical read: The overall signal is “low-stakes, low-upside”: mostly neutral outcomes, occasional mild benefits, occasional mild flares.
Practical Caution Signal
Even if it’s generally discussed as lower risk, ginkgo isn’t guaranteed neutral. It can affect vascular tone and CNS arousal in some people, and it has blood-thinning/bleeding-risk considerations (especially if combined with anticoagulants/antiplatelet drugs or around surgery). For a PFS/PSSD/PAS audience, the most conservative framing is: if someone wants to trial it for ED support, keep it as a single-variable test, watch for headaches/anxiety/sleep disruption, and discontinue if it consistently worsens symptoms.
Evidence Basis
General herbal pharmacology and clinical literature on ginkgo for cognition/circulation; anecdotal community reports (online forums, self-reports). No controlled studies establishing benefit for PFS/PSSD/PAS-specific outcomes.